Continuous Processing Technology

What is Continuous Processing?

Continuous Processes Operate All Steps Simultaneously

What Can a PAK System Do?

A Single PAK System Can Perform Any 4 Unit Operations Continuously

Including the Addition of 4 Buffer Streams

And Stay within an Ideal Window for All Critical Parameters

In any Order you Choose

How do PAK Systems Control Flow?

PAK Systems Have Fully Automated Real-Time Adaptive Control

Watch the PAK Control Strategy

How is a PAK System Economical?

PAK Systems Cycle Columns to their Maximum Value

Batch vs. Continuous Processing Resin Costs

Scale	Batch Column-Pack Cost	Continuous (Dual Column) Column-Pack Cost
50 L Bioreactor / day	$103k (20cm column)	$3.1k (2 x 5 cm columns)
500 L Bioreactor / day	$1.03M (60cm column)	$31k (2 x 10 cm columns)
5000 L Bioreactor / day	$10.3M (2m column)	$310k (2 x 45 cm columns)

A PAK System Will Reduce Resin Costs by 33 TIMES over batch processing

Valuable Innovation for the Industry

Company-Registered Intellectual Property

U.S. Granted Patent	10,981,905	THERAPEUTIC PROTEIN FLOW KIT FOR A CONTINUOUS PURIFICATION SYSTEM
U.S. Trademark Registration	6441788	PAK BioSolutions

Other U.S. and International patents pending.